Detection of Clinically Significant Warm Reactive Anti-A1 in a Post Red Blood Cells Transfusion Patient with Acute Lymphoblastic Leukemia

The purpose of this article is to report that some anti-A1 react at 37°C are IgG antibodies and clinically significant, as they can cause the destruction a proportion A1 cells in vivo following transfusion red blood cells. Therefore, when serum an individual contains anti-A1, further testing plasma against group A1, A2, O by referencing lectin (Dolichos biflorus lectin) must be performed. Confirming specificity also important selecting appropriate for transfusion. ABO naturally occurring activate complement cascade, making them more likely severe reactions compared other RBC antigens.